A team of geneticists at the Broad Institute in Cambridge Massachusetts is investigating how DNA differs among human genomes from around the world. Over the course of human history, naturally, different mutations have sprung up in different regions, and became prevalent or not depending on local conditions. Having identified region-specific pieces of DNA, the interesting part is then trying to figure out what those pieces of DNA do.
An example under current investigation is the EDAR370A gene, which is found in Asian people, and is thought to have arisen in China 30,000 years ago. To determine EDAR370A’s thing, the experimenters snipped it out, pasted it into mouse embryos, and waited to see how the mice turned out. They grew up to have Continue reading